ESHRE PGD Consortium Best practice guidelines for clinical preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS)
Authors: Thornhill, A.R.1; deDie-Smulders, C.E.2; Geraedts, J.P.2; Harper, J.C.3; Harton, G.L.4; Lavery, S.A.5; Moutou, C.6; Robinson, M.D.7; Schmutzler, A.G.8; Scriven, P.N.9; Sermon, K.D.10; Wilton, L.11
Source: Human Reproduction, Volume 20, Number 1, 1 January 2005 , pp. 35-48(14)
Publisher: Oxford University Press
Abstract:Among the many educational materials produced by the European Society of Human Reproduction and Embryology (ESHRE) are guidelines. ESHRE guidelines may be developed for many reasons but their intent is always to promote best quality practices in reproductive medicine. In an era in which preimplantation genetic diagnosis (PGD) has become a reality, we must strive to maintain its efficacy and credibility by offering the safest and most effective treatment available. The dominant motivators for the development of current comprehensive guidelines for best PGD practice were (i) the absence of guidelines and/or regulation for PGD in many countries and (ii) the observation that no consensus exists on many of the clinical and technical aspects of PGD. As a consequence, the ESHRE PGD Consortium undertook to draw up guidelines aimed at giving information, support and guidance to potential, fledgling and established PGD centres. The success of a PGD treatment cycle is the result of great attention to detail. We have strived to provide a similar level of detail in this document and hope that it will assist staff in achieving the best clinical outcome for their patients.
Document Type: Research article
Affiliations: 1: Section of Reproductive Endocrinology and Infertility, Mayo Clinic, College of Medicine Rochester, MN, USA, 2: Department of Clinical Genetics, University Hospital Maastricht, Maastricht, The Netherlands, 3: Department of Obstetrics and Gynaecology, University College, London, 4: Genetics and IVF Institute, Fairfax, VA, USA, 5: Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Hammersmith Hospital, 6: Service de Biologie de la Reproduction, SIHCUS-CMCO, 19 Rue Louis Pasteur, BP120, 67303 Schiltigheim, France, 7: The Leeds PGD Centre, Assisted Conception Unit, Leeds General Infirmary, Leeds, UK, 8: Section of Reproductive Medicine, University of Kiel, Germany, 9: Department of Cytogenetics, and Centre for Preimplantation Genetic Diagnosis, Guy's and St. Thomas' NHS Trust, Guy's Hospital, London, 10: Centre for Medical Genetics, Dutch-speaking Brussels Free University, Brussels, Belgium and 11: Melbourne IVF, 320 Victoria Parade, 3002 East Melbourne VIC, Australia
Publication date: 2005-01-01
- Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.
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- In this Subject: Anatomy & Physiology , Obstetrics & Gynecology
- By this author: Thornhill, A.R. ; deDie-Smulders, C.E. ; Geraedts, J.P. ; Harper, J.C. ; Harton, G.L. ; Lavery, S.A. ; Moutou, C. ; Robinson, M.D. ; Schmutzler, A.G. ; Scriven, P.N. ; Sermon, K.D. ; Wilton, L.