Best site for embryo transfer: the upper or lower half of endometrial cavity?
Source: Human Reproduction, Volume 19, Number 8, August 2004 , pp. 1785-1790(6)
Publisher: Oxford University Press
Abstract:BACKGROUND: The objective of the present study was to determine the importance of the site of embryo transfer (upper or lower half endometrial cavity) on implantation and clinical pregnancy rates. METHODS: A total of 400 transfers guided by ultrasound were randomly assigned to two groups according to the distance between the uterine fundus and the catheter tip at the time of embryo placement. Group I (n=200) consisted of transfers corresponding to a distance of <50% of the endometrial cavity length (ECL), i.e. transfer in upper half of the cavity; and group II (n=200) consisted of transfers corresponding to a distance of ≥50%, of the ECL, i.e. transfer in lower half of cavity. The Student's t-test, Mann–Whitney test and Fisher's exact test were used where appropriate. RESULTS: The general characteristics of the study population and the main transfer cycle characteristics had an equal distribution (P>0.05) between groups I and II. No significant difference in implantation or pregnancy rates was observed between groups I and II. CONCLUSION: The implantation or pregnancy rates were similar whether the embryos were deposited in the upper or lower half of the endometrial cavity.
Document Type: Research Article
Affiliations: 1: Center for Human Reproduction, Sinhá Junqueira Maternity Foundation, Ribeirão Preto, SP and 2: Department of Gynecology and Obstetrics, Faculty of Medicine of Botucatu, UNESP, Botucatu, SP, Brazil
Publication date: August 2004
- Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.