Andrology. Time to pregnancy in relation to semen quality assessed by CASA before and after sperm separation
Source: Human Reproduction, Volume 17, Number 1, January 2002 , pp. 173-177(5)
Publisher: Oxford University Press
Abstract:BACKGROUND: In order to provide a reference for infertile men, we defined normal values of semen quality in a population of fertile men, using computer-assisted semen analysis (CASA) before and after sperm separation. Additionally, we investigated the relationship between semen quality and time to pregnancy (TTP). METHODS AND RESULTS: Semen samples were obtained from 315 proven fertile men. The median sperm concentration in fresh samples was 107×106/ml (5–95 percentiles: 16–322×106/ml), the median percentage of motile sperm cells was 65% (14–87%) and the median percentage of progressively motile cells was 37% (5–64%). After density gradient sperm separation, the median total sperm count was 46×106 (4–350×106), the median percentage of motile sperm cells was 77% (16–95%) and the median percentage of progressively motile cells was 63% (11–84%). No significant associations were found between TTP and sperm counts or sperm motility, either before or after sperm separation. This may be due in part to the fact that the study comprised couples with proven fertility. CONCLUSION: We have defined semen parameters, including the results of density gradient separation, in a population of normal fertile men which may be of interest in the evaluation of semen samples from infertile men.
Document Type: Research Article
Publication date: 2002-01-01
- Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.