Authors: Soysal, Mehmet Emin¹; Soysal, Seyide¹; Vıcdan, Kubilay²; Ozer, Suzan³

Source: Human Reproduction, Volume 16, Number 5, May 2001 , pp. 931-939(9)

Publisher: Oxford University Press

Abstract:

Following identification of the proportion of pelvic congestion among symptomatic patients complaining of chronic pelvic pain, and in a totally asymptomatic group of patients requesting tubal ligation, the efficiency of goserelin acetate versus medroxyprogesterone acetate was compared objectively using pelvic venogram scores, and subjectively by symptom resolution, improvement of psychological status and sexual functioning in a prospective randomized trial in 47 patients with pure pelvic congestion syndrome. Patients received either goserelin acetate (3.6 mg/month for 6 months) or medroxyprogesterone acetate (MPA; 30 mg/day for 6 months). Among patients with chronic pelvic pain, those with pure pelvic congestion were mostly parous, had the most severe pelvic signs and symptom scores, lowest rates of sexual functioning, and higher states of anxiety and depression as compared with others. At 1 year after treatment, goserelin remained superior to MPA in terms of pelvic venographic improvement as an objective measure. In alleviation of signs and symptomatology, improvement of sexual functioning and reduction of anxiety and depressive states as subjective measures, goserelin acetate achieved a statistically significant advantage (P = 0.0001) compared with MPA.

Keywords: goserelin acetate; medroxyprogesterone acetate; pelvic congestion syndrome

Document Type: Research article

Affiliations: 1: Department of Obstetrics and Gynecology, Pamukkale University Medical Center, Denizli, 2: Department of Obstetrics and Gynecology, Bayındır Medical Center, Ankara and 3: Department of Psychiatry, Hacettepe University School of Medicine, 06200, Ankara, Turkey

Publication date: 2001-05-01

More about this publication?

• Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.

Related content

• In this: publication
• By this: publisher
• In this Subject: Anatomy & Physiology ,  Obstetrics & Gynecology
• By this author: Soysal, Mehmet Emin ;  Soysal, Seyide ;  Vıcdan, Kubilay ;  Ozer, Suzan

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers