Infertility. Obstetric and neonatal outcome in women with a history of recurrent miscarriage: a cohort study

Authors: Jivraj S.¹; Anstie B.¹; Cheong Y-C.¹; Fairlie F.M.¹; Laird S.M.²; Li T.C.¹

Source: Human Reproduction, Volume 16, Number 1, January 2001 , pp. 102-106(5)

Publisher: Oxford University Press

Abstract:

Obstetric and neonatal outcomes of women who had a history of recurrent miscarriage were compared with a control population from 1 January 1992 to 30 June 1998. Amongst a total of 162 pregnancies which progressed beyond 24 weeks gestation in women with a history of recurrent miscarriage, there were four perinatal deaths and 16 babies were admitted to the special care baby unit. The rates of preterm delivery (13%), small-for-gestational-age (13%), perinatal loss (2.5%) and Caesarean section (36%) were significantly (P < 0.05) higher than those of the control group (3.9, 2.1, 1 and 16.7% respectively). The ratio of male to female babies was equal. There was no significant difference in the incidence of hypertension or diabetes between the two groups. Patients with recurrent miscarriage represent a population at high risk of obstetric problems and close surveillance in the antenatal period is therefore required.

Keywords: growth retardation; perinatal outcome; pre-eclampsia; recurrent miscarriage

Document Type: Original article

Affiliations: 1: Jessop Hospital for Women and 2: Division of Biomedical Sciences, Sheffield Hallam University, Sheffield, UK

Publication date: 2001-01-01

• Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.

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• In this Subject: Anatomy & Physiology ,  Obstetrics & Gynecology
• By this author: Jivraj S. ;  Anstie B. ;  Cheong Y-C. ;  Fairlie F.M. ;  Laird S.M. ;  Li T.C.

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