Embryology. Successful pregnancy following blastocyst vitrification: Case report
Authors: Yokota, Y.; Sato, S.; Yokota, M.; Ishikawa, Y.; Makita, M.; Asada, T.
Source: Human Reproduction, Volume 15, Number 8, August 2000 , pp. 1802-1803(2)
Publisher: Oxford University Press
Abstract:A 32 year old woman and her 32 year old spouse were referred to our IVF programme. Following recovery of 12 mature oocytes, nine were fertilized following conventional IVF. Three fresh embryos were transferred to the uterus, but all failed to result in pregnancy. Six supernumerary embryos were cultured in vitro until day 5 in order to create blastocysts. Two grew to the blastocyst stage and were vitrified using a modification of a previous method. Two blastocysts survived the freeze–thaw process and were transferred to the patient's uterus during a natural cycle, 3 months after the previous retrieval cycle. Implantation resulted in a healthy pregnancy; delivery is expected in June 2000. This report documents the first successful pregnancy in Japan, achieved via blastocyst vitrification.
Document Type: Research Article
Affiliations: Yokota Ob/Gyn Clinic, 1-16-5, Shimokoide, Maebashi, Gunma 371-0031, and
Publication date: August 2000
- Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.