Case report. Medical management of interstitial ectopic pregnancy: a case report and literature review
Source: Human Reproduction, Volume 13, Number 7, July 1998 , pp. 1981-1986(6)
Publisher: Oxford University Press
Abstract:Recent reports describe successful treatment of interstitial ectopic pregnancies using methotrexate. While the number of reported cases is increasing, no consensus exists regarding the management of this complication of pregnancy. We present the successful use of combined systemic and direct intrasac injection of methotrexate for an interstitial pregnancy with the highest yet reported initial β-human chorionic gonadotrophin concentration (102 000 mIU/ml). We also describe the use of Doppler ultrasound for monitoring treatment progression. Through a review of the current literature, we propose to facilitate management decisions and increase outcome success by summarizing previously reported treatment regimens and by describing enhanced parameters for patient selection and monitoring.
Keywords:cornual pregnancy/interstitial pregnancy/medical management/methotrexate
Document Type: Research Article
Affiliations: 1: Division of Reproductive Endocrinology and Infertility and 2: Department of Gynecology and Obstetrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA 3: Division of Maternal Fetal Medicine,
Publication date: 1998-07-01
- Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.