Relationships between motility parameters, morphology and acrosomal status of human spermatozoa
Authors: Parinaud, Jean; Vieitez, Gérard; Moutaffian, Hélène; Richoilley, Gérard; Milhet, Pierrette
Source: Human Reproduction, Volume 11, Number 6, June 1996 , pp. 1240-1243(4)
Publisher: Oxford University Press
Abstract:A total of 130 semen samples were examined for motility (by computer-assisted sperm analysis), morphology and acrosomal status. A high positive correlation was found between percentages of normal forms and progressive motility in the whole semen (r = 0.539, P < 0.0001) as well as in the Percoll fraction (r = 0.702, P < 0.0001). Among the specific abnormalities, acrosome defects were most highly correlated with progressive motility (r = −0.492, P < 0.0001, in the Percoll fraction). The percentage of total spontaneously acrosome-reacted spermatozoa in the Percoll fraction was negatively correlated with the progressive motility (r = −0.499, P < 0.0001) and with the percentage of normal forms (r = −0.430, P < 0.0001). Surprisingly, the percentage of total spontaneously acrosome-reacted spermatozoa was poorly linked with head abnormalities but displayed significant positive correlations with the percentages of bent tails (r = 0359, P < 0.0001) and of coiled tails (r = 0371, P < 0.0001). These data suggest that sperm defects are often linked together, reflecting spermiogenesis and/or epididymal dysfunctions.
Document Type: Research article
Publication date: 1996-06-01
- Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues. Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues. The highest scientific and editorial standard is maintained throughout the journal along with a rapid rate of publication.