Persistence of upper respiratory tract infections in a cohort followed from childhood to adulthood
Authors: Rovers, Maroeska M; Balemans, Walter A F; Sanders, Elisabeth A M; van der Ent, Cornelis K; Zielhuis, Gerhard A; Schilder, Anne G M
Source: Family Practice, Volume 23, Number 3, June 2006 , pp. 286-290(5)
Publisher: Oxford University Press
Abstract:Objective. To assess (1) prevalences of recurrent URTIs (rURTIs) and relapsing/persistent rURTIs and associated medical consumption between 0 and 21 years of age and (2) whether rURTIs experienced in early life predispose to upper airway disease later in life.
Methods. A cohort of all children born in Nijmegen, The Netherlands, between September 1982 and September 1983, was assessed repeatedly from 2 to 21 years of age with questionnaires regarding infections of the upper respiratory tract (URTIs), use of antibiotics, ENT operations and known risk factors for URTIs.
Results. One hundred and sixty-one of the 693 cohort member (23%) suffered from relapsing rURTIs between 0 and 21 years of age, whereas only 7 (1%) suffered from persistent rURTIs throughout this period. Two hundred and six (30%) had used antibiotics more than once; and 220 (32%) had undergone at least one ENT operation. Of the 166 participants with rURTI between 8 and 21 years, 140 (84%) had had rURTI before.
Conclusions. rURTIs are highly prevalent throughout early life and associated medical consumption is substantial. The challenge therefore is to develop therapeutic/preventive strategies that will prevent rURTIs in the first years of life.
Document Type: Research Article
Publication date: 2006-06-01
- Family Practice is an international journal aimed at practitioners, teachers and researchers in the fields of family medicine, general practice and primary care in both developed and developing countries.