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The leading journal in its field, Bioinformatics publishes the highest quality scientific papers and review articles of interest to academic and industrial researchers. Its main focus is on new developments in genome bioinformatics and computational biology. Two distinct sections within the journal - Discovery Notes and Application Notes- focus on shorter papers; the former reporting biologically interesting discoveries using computational methods, the latter exploring the applications used for experiments.

Publisher: Oxford University Press

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Volume 28, Number 3, 1 February 2012

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A simple statistical test to infer the causality of target/phenotype correlation from small molecule phenotypic screens
pp. 301-305(5)
Authors: Wei, Xin; Hoffman, Ann F.; Hamilton, Shannon M.; Xiang, Qing; He, Yang; So, W. Venus; So, Sung-Sau; Mark, David

InFiRe a novel computational method for the identification of insertion sites in transposon mutagenized bacterial genomes
pp. 306-310(5)
Authors: Shevchuk, Olga; Roselius, Louisa; Gnther, Gabriele; Klein, Johannes; Jahn, Dieter; Steinert, Michael; Mnch, Richard

SomaticSniper: identification of somatic point mutations in whole genome sequencing data
pp. 311-317(7)
Authors: Larson, David E.; Harris, Christopher C.; Chen, Ken; Koboldt, Daniel C.; Abbott, Travis E.; Dooling, David J.; Ley, Timothy J.; Mardis, Elaine R.; Wilson, Richard K.; Ding, Li

Detection of microRNAs in color space
pp. 318-323(6)
Authors: Marco, Antonio; Griffiths-Jones, Sam

SCPC: a method to structurally compare protein complexes
pp. 324-330(7)
Authors: Koike, Ryotaro; Ota, Motonori

HydroPaCe: understanding and predicting cross-inhibition in serine proteases through hydrophobic patch centroids
pp. 342-349(8)
Authors: Gonalves-Almeida, V. M.; Pires, D. E. V.; de Melo-Minardi, R. C.; da Silveira, C. H.; Meira, W.; Santoro, M. M.

Inhibition of HIV-1 protease: the rigidity perspective
pp. 350-357(8)
Authors: Heal, J. W.; Jimenez-Roldan, J. E.; Wells, S. A.; Freedman, R. B.; Rmer, R. A.

M3: an improved SNP calling algorithm for Illumina BeadArray data
pp. 358-365(8)
Authors: Li, Gengxin; Gelernter, Joel; Kranzler, Henry R.; Zhao, Hongyu

Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data
pp. 373-380(8)
Authors: Karnovsky, Alla; Weymouth, Terry; Hull, Tim; Tarcea, V. Glenn; Scardoni, Giovanni; Laudanna, Carlo; Sartor, Maureen A.; Stringer, Kathleen A.; Jagadish, H. V.; Burant, Charles; Athey, Brian; Omenn, Gilbert S.

Minimal cut sets in a metabolic network are elementary modes in a dual network
pp. 381-387(7)
Authors: Ballerstein, Kathrin; von Kamp, Axel; Klamt, Steffen; Haus, Utz-Uwe

Construction and completion of flux balance models from pathway databases
pp. 388-396(9)
Authors: Latendresse, Mario; Krummenacker, Markus; Trupp, Miles; Karp, Peter D.

Integrating human and murine anatomical gene expression data for improved comparisons
pp. 397-402(6)
Authors: Jimnez-Lozano, Natalia; Segura, Joan; Macas, Jos Ramn; Vega, Juanjo; Carazo, Jos Mara

SNPxGE2: a database for human SNPcoexpression associations
pp. 403-410(8)
Authors: Wang, Yupeng; Joseph, Sandeep J.; Liu, Xinyu; Kelley, Michael; Rekaya, Romdhane

The Virtual Fly Brain browser and query interface
pp. 411-415(5)
Authors: Milyaev, Nestor; Osumi-Sutherland, David; Reeve, Simon; Burton, Nicholas; Baldock, Richard A.; Armstrong, J. Douglas

PGAP: pan-genomes analysis pipeline
pp. 416-418(3)
Authors: Zhao, Yongbing; Wu, Jiayan; Yang, Junhui; Sun, Shixiang; Xiao, Jingfa; Yu, Jun

GenomeRunner: automating genome exploration
pp. 419-420(2)
Authors: Dozmorov, Mikhail G.; Cara, Lukas R.; Giles, Cory B.; Wren, Jonathan D.

Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant tools
pp. 421-422(2)
Authors: San Lucas, F. Anthony; Wang, Gao; Scheet, Paul; Peng, Bo

Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data
pp. 423-425(3)
Authors: Boeva, Valentina; Popova, Tatiana; Bleakley, Kevin; Chiche, Pierre; Cappo, Julie; Schleiermacher, Gudrun; Janoueix-Lerosey, Isabelle; Delattre, Olivier; Barillot, Emmanuel

NRPSsp: non-ribosomal peptide synthase substrate predictor
pp. 426-427(2)
Authors: Prieto, Carlos; Garca-Estrada, Carlos; Lorenzana, Diego; Martn, Juan Francisco

B-SOLANA: an approach for the analysis of two-base encoding bisulfite sequencing data
pp. 428-429(2)
Authors: Kreck, Benjamin; Marnellos, George; Richter, Julia; Krueger, Felix; Siebert, Reiner; Franke, Andre

RRBSMAP: a fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing
pp. 430-432(3)
Authors: Xi, Yuanxin; Bock, Christoph; Mller, Fabian; Sun, Deqiang; Meissner, Alexander; Li, Wei

Identification and removal of ribosomal RNA sequences from metatranscriptomes
pp. 433-435(3)
Authors: Schmieder, Robert; Lim, Yan Wei; Edwards, Robert

SitePainter: a tool for exploring biogeographical patterns
pp. 436-438(3)
Authors: Gonzalez, Antonio; Stombaugh, Jesse; Lauber, Christian L.; Fierer, Noah; Knight, Rob

DMAN: a Java tool for analysis of multi-well differential scanning fluorimetry experiments
pp. 439-440(2)
Authors: Wang, Conan K.; Weeratunga, Saroja K.; Pacheco, Chris M.; Hofmann, Andreas

MTBindingSim: simulate protein binding to microtubules
pp. 441-443(3)
Authors: Philip, Julia T.; Pence, Charles H.; Goodson, Holly V.

GWAtoolbox: an R package for fast quality control and handling of genome-wide association studies meta-analysis data
pp. 444-445(2)
Authors: Fuchsberger, Christian; Taliun, Daniel; Pramstaller, Peter P.; Pattaro, Cristian

An infrastructure for ontology-based information systems in biomedicine: RICORDO case study
pp. 448-450(3)
Authors: Wimalaratne, Sarala M.; Grenon, Pierre; Hoehndorf, Robert; Gkoutos, Georgios V.; de Bono, Bernard

seeQTL: a searchable database for human eQTLs
pp. 451-452(2)
Authors: Xia, Kai; Shabalin, Andrey A.; Huang, Shunping; Madar, Vered; Zhou, Yi-Hui; Wang, Wei; Zou, Fei; Sun, Wei; Sullivan, Patrick F.; Wright, Fred A.

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