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The leading journal in its field, Bioinformatics publishes the highest quality scientific papers and review articles of interest to academic and industrial researchers. Its main focus is on new developments in genome bioinformatics and computational biology. Two distinct sections within the journal - Discovery Notes and Application Notes- focus on shorter papers; the former reporting biologically interesting discoveries using computational methods, the latter exploring the applications used for experiments.

Publisher: Oxford University Press

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Volume 21, Number 7, 01 April 2005

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Profile-based detection of microRNA precursors in animal genomes
pp. 841-845(5)
Authors: Legendre, Matthieu; Lambert, André; Gautheret, Daniel

ColorHOR—novel graphical algorithm for fast scan of alpha satellite higher-order repeats and HOR annotation for GenBank sequence of human genome
pp. 846-852(7)
Authors: Paar, Vladimir; Pavin, Nenad; Rosandicacute, Marija; Glunccaronicacute, Matko; Basar, Ivan; Pezer, Robert; Zcaroninicacute, Sonja Durajlija

BACCardI—a tool for the validation of genomic assemblies, assisting genome finishing and intergenome comparison
pp. 853-859(7)
Authors: Bartels, Daniela; Kespohl, Sebastian; Albaum, Stefan; Drüke, Tanja; Goesmann, Alexander; Herold, Julia; Kaiser, Olaf; Pühler, Alfred; Pfeiffer, Friedhelm; Raddatz, Günter; Stoye, Jens; Meyer, Folker; Schuster, Stephan C.

Theoretical and practical advances in genome halving
pp. 869-879(11)
Authors: Yin, Peng; Hartemink, Alexander J.

Operon prediction without a training set
pp. 880-888(9)
Authors: Westover, B. P.; Buhler, J. D.; Sonnenburg, J. L.; Gordon, J. I.

A parallel graph decomposition algorithm for DNA sequencing with nanopores
pp. 889-896(8)
Authors: Bokhari, Shahid H.; Sauer, Jon R.

Accurate identification of alternatively spliced exons using support vector machine
pp. 897-901(5)
Authors: Dror, Gideon; Sorek, Rotem; Shamir, Ron

Fast and accurate database homology search using upper bounds of local alignment scores
pp. 912-921(10)
Authors: Itoh, Masumi; Goto, Susumu; Akutsu, Tatsuya; Kanehisa, Minoru

Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites
pp. 922-931(10)
Authors: Sabatti, Chiara; Rohlin, Lars; Lange, Kenneth; Liao, James C.

Rapid motif-based prediction of circular permutations in multi-domain proteins
pp. 932-937(6)
Authors: Weiner, January; Thomas, Geraint; Bornberg-Bauer, Erich

Predicting protein localization in budding Yeast
pp. 944-950(7)
Authors: Chou, Kuo-Chen; Cai, Yu-Dong

Protein homology detection by HMM–HMM comparison
pp. 951-960(10)
Authors: Söding, Johannes

DPRml: distributed phylogeny reconstruction by maximum likelihood
pp. 969-974(6)
Authors: Keane, T. M.; Naughton, T. J.; Travers, S. A. A.; McInerney, J. O.; McCormack, G. P.

An alternative model of amino acid replacement
pp. 975-980(6)
Authors: Crooks, Gavin E.; Brenner, Steven E.

A new approach to prediction of short-range conformational propensities in proteins
pp. 981-987(7)
Authors: Gront, Dominik; Kolinski, Andrzej

PDBML: the representation of archival macromolecular structure data in XML
pp. 988-992(5)
Authors: Westbrook, John; Ito, Nobutoshi; Nakamura, Haruki; Henrick, Kim; Berman, Helen M.

Statistical analysis of domains in interacting protein pairs
pp. 993-1001(9)
Authors: Nye, Tom M. W.; Berzuini, Carlo; Gilks, Walter R.; Babu, M. Madan; Teichmann, Sarah A.

Predicting fold novelty based on ProtoNet hierarchical classification
pp. 1020-1027(8)
Authors: Kifer, Ilona; Sasson, Ori; Linial, Michal

Solving and analyzing side-chain positioning problems using linear and integer programming
pp. 1028-1039(12)
Authors: Kingsford, Carleton L.; Chazelle, Bernard; Singh, Mona

Local correlation of expression profiles with gene annotations—proof of concept for a general conciliatory method
pp. 1037-1045(9)
Authors: Pinto, F. R.; Cowart, L. Ashley; Hannun, Yusuf A.; Rohrer, B.; Almeida, J. S.

Superior feature-set ranking for small samples using bolstered error estimation
pp. 1046-1054(9)
Authors: Sima, Chao; Braga-Neto, Ulisses; Dougherty, Edward R.

Extracting relations between promoter sequences and their strengths from microarray data
pp. 1062-1068(7)
Authors: Kiryu, Hisanori; Oshima, Taku; Asai, Kiyoshi

Clustering of gene expression data using a local shape-based similarity measure
pp. 1069-1077(9)
Authors: Balasubramaniyan, Rajarajeswari; Hüllermeier, Eyke; Weskamp, Nils; Kämper, Jörg

Normalization of two-channel microarray experiments: a semiparametric approach
pp. 1078-1083(6)
Authors: Eckel, J. E.; Gennings, C.; Therneau, T. M.; Burgoon, L. D.; Boverhof, D. R.; Zacharewski, T. R.

GoArrays: highly dynamic and efficient microarray probe design
pp. 1094-1103(10)
Authors: Rimour, Sébastien; Hill, David; Militon, Cécile; Peyret, Pierre

Classification using partial least squares with penalized logistic regression
pp. 1104-1111(8)
Authors: Fort, Gersende; Lambert-Lacroix, Sophie

Validation of alternative methods of data normalization in gene co-expression studies
pp. 1112-1120(9)
Authors: Reverter, Antonio; Barris, Wes; McWilliam, Sean; Byrne, Keren A.; Wang, Yong H.; Tan, Siok H.; Hudson, Nick; Dalrymple, Brian P.

Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression
pp. 1129-1137(9)
Authors: Ben-Shaul, Yoram; Bergman, Hagai; Soreq, Hermona

Quantile smoothing of array CGH data
pp. 1146-1153(8)
Authors: Eilers, Paul H. C.; de Menezes, Renée X.

Inference of S-system models of genetic networks using a cooperative coevolutionary algorithm
pp. 1154-1163(10)
Authors: Kimura, Shuhei; Ide, Kaori; Kashihara, Aiko; Kano, Makoto; Hatakeyama, Mariko; Masui, Ryoji; Nakagawa, Noriko; Yokoyama, Shigeyuki; Kuramitsu, Seiki; Konagaya, Akihiko

Comparison of computational methods for the identification of cell cycle-regulated genes
pp. 1164-1171(8)
Authors: de Lichtenberg, Ulrik; Jensen, Lars Juhl; Jensen, Thomas S.; Bork, Peer; Brunak, Søren

Finding regulatory modules through large-scale gene-expression data analysis
pp. 1172-1179(8)
Authors: Kloster, M.; Tang, C.; Wingreen, N.S.

Metabolic pathway analysis web service (Pathway Hunter Tool at CUBIC)
pp. 1189-1193(5)
Authors: Rahman, S. A.; Advani, P.; Schunk, R.; Schrader, R.; Schomburg, Dietmar

Intervention in context-sensitive probabilistic Boolean networks
pp. 1211-1218(8)
Authors: Pal, Ranadip; Datta, Aniruddha; Bittner, Michael L.; Dougherty, Edward R.

Automatic extraction of gene/protein biological functions from biomedical text
pp. 1227-1236(10)
Authors: Koike, Asako; Niwa, Yoshiki; Takagi, Toshihisa

In silico gene function prediction using ontology-based pattern identification
pp. 1237-1245(9)
Authors: Zhou, Yingyao; Young, Jason A.; Santrosyan, Andrey; Chen, Kaisheng; Yan, S. Frank; Winzeler, Elizabeth A.

ISYMOD: a knowledge warehouse for the identification, assembly and analysis of bacterial integrated systems
pp. 1246-1256(11)
Authors: Chabalier, Julie; Capponi, Cécile; Quentin, Yves; Fichant, Gwennaele

CRAVE: a database, middleware and visualization system for phenotype ontologies
pp. 1257-1262(6)
Authors: Gkoutos, Georgios V.; Green, Eain C.J.; Greenaway, Simon; Blake, Andrew; Mallon, Ann-Marie; Hancock, John M.

Primaclade—a flexible tool to find conserved PCR primers across multiple species
pp. 1263-1264(2)
Authors: Gadberry, Michael D.; Malcomber, Simon T.; Doust, Andrew N.; Kellogg, Elizabeth A.

SABmark—a benchmark for sequence alignment that covers the entire known fold space
pp. 1267-1268(2)
Authors: Van Walle, Ivo; Lasters, Ignace; Wyns, Lode

NetAcet: prediction of N-terminal acetylation sites
pp. 1269-1270(2)
Authors: Kiemer, Lars; Bendtsen, Jannick Dyrløv; Blom, Nikolaj

Multiple sequence alignment with user-defined constraints at GOBICS
pp. 1271-1273(3)
Authors: Morgenstern, Burkhard; Werner, Nadine; Prohaska, Sonja J.; Steinkamp, Rasmus; Schneider, Isabelle; Subramanian, Amarendran R.; Stadler, Peter F.; Weyer-Menkhoff, Jan

SlidingBayes: exploring recombination using a sliding window approach based on Bayesian phylogenetic inference
pp. 1274-1275(2)
Authors: Paraskevis, D.; Deforche, K.; Lemey, P.; Magiorkinis, G.; Hatzakis, A.; Vandamme, A.-M.

TMDET: web server for detecting transmembrane regions of proteins by using their 3D coordinates
pp. 1276-1277(2)
Authors: Tusnády, Gábor E.; Dosztányi, Zsuzsanna; Simon, István

CyDAS: a cytogenetic data analysis system
pp. 1282-1283(2)
Authors: Hiller, Bernhard; Bradtke, Jutta; Balz, Harald; Rieder, Harald

Grid Cellware: the first grid-enabled tool for modelling and simulating cellular processes
pp. 1284-1287(4)
Authors: Dhar, Pawan K.; Meng, Tan Chee; Somani, Sandeep; Ye, Li; Sakharkar, Kishore; Krishnan, Arun; Ridwan, Azmi B.M.; Wah, Sebastian Ho Kok; Chitre, Mandar; Hao, Zhu

hp-DPI: Helicobacter pylori Database of Protein Interactomes—embracing experimental and inferred interactions
pp. 1288-1290(3)
Authors: Lin, Chung-Yen; Chen, Chia-Ling; Cho, Chi-Shiang; Wang, Li-Ming; Chang, Chia-Ming; Chen, Pao-Yang; Lo, Chen-Zen; Hsiung, Chao A.

BRAGI: linking and visualization of database information in a 3D viewer and modeling tool
pp. 1291-1293(3)
Authors: Reichelt, Joachim; Dieterich, Guido; Kvesic, Marsel; Schomburg, Dietmar; Heinz, Dirk W.

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