Eradication and cessation of programmes

Author: P D Minor

Source: British Medical Bulletin, Volume 62, Number 1, July 2002 , pp. 213-224(12)

Buy & download fulltext article:

Price: $42.29 plus tax (Refund Policy)

Abstract:

Eradication of disease requires the eradication of the causative agent. Smallpox is the only human disease knowingly eradicated so far and, while poliomyelitis is likely to be the second, they present very different problems. All smallpox infections were apparent when significantly infectious, the vaccine was very easy to deliver and its effects easy to monitor, and it was incapable of causing the disease it was intended to prevent. In contrast, most poliovirus infections are silent, vaccination leaves no outward sign, and there is a low, but real, incidence of vaccine-associated poliomyelitis. While smallpox was eradicated by containment of infections by quarantine and vaccination, poliomyelitis requires mass vaccination campaigns to break virus transmission. Moreover, in contrast to smallpox, the strategies for stopping polio vaccination are still under discussion. The polio eradication programme on the other hand has made and continues to make strides towards its goal, and is a major triumph of public health interventions.

Document Type: Research article

Affiliations: 1: Division of Virology, National Institute for Biological Standards and Control, Potters Bar, Hertfordshire, UK

Publication date: 2002-07-01

More about this publication?

British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors and medical students in both developed and developing countries.