Abstract:

Persistent viruses present some particular problems for vaccine design. As for acute non-persistent viruses, the prime goal of a vaccine should be to prevent primary infection. Vaccines might also be used to modify the course of established persistent virus infections – so-called postinfective immunisation. This chapter deals with selected persistent DNA viruses, in particular the human herpes viruses.

Document Type: Research article

Affiliations: 1: Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, UK