Vaccines against persistent DNA virus infections

Authors: M R Wills1; A J Carmichael1; J G P Sissons1

Source: British Medical Bulletin, Volume 62, Number 1, July 2002 , pp. 125-138(14)

Publisher: Oxford University Press

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Abstract:

Persistent viruses present some particular problems for vaccine design. As for acute non-persistent viruses, the prime goal of a vaccine should be to prevent primary infection. Vaccines might also be used to modify the course of established persistent virus infections – so-called postinfective immunisation. This chapter deals with selected persistent DNA viruses, in particular the human herpes viruses.

Document Type: Research article

Affiliations: 1: Department of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, UK

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