Congenital diaphragmatic hernia in the neonate
Authors: King, Hannah; Booker, Peter D
Source: BJA - CEPD Reviews, Volume 5, Number 5, October 2005 , pp. 171-174(4)
Publisher: Oxford University Press
Abstract:The prevalence of congenital diaphragmatic hernia (CDH) ranges between 1:2000 and 1:4000 live births; it accounts for 8% of all major congenital anomalies. Recurrence risk for a subsequent pregnancy is estimated at 2%.1 Approximately 90% of diaphragmatic defects occur posterolaterally and 80% are left-sided. The severity of the condition varies widely, the degree of pulmonary hypoplasia and pulmonary hypertension largely determining outcome. After recent advances in the care of these patients, several centres are now reporting survival rates >80%. This improved survival is ascribed to increased knowledge of the pathophysiology of the condition and, consequently, better perioperative management.
Document Type: Research article
Publication date: 2005-10-01