Post-translational regulation of FOXO
Authors: Xie, Qi; Chen, Jing; Yuan, Zengqiang
Source: Acta Biochimica et Biophysica Sinica, Volume 44, Number 11, November 2012 , pp. 897-901(5)
Publisher: Oxford University Press
Abstract:The Forkhead box O (FOXO) family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post-translational modifications, which are closely related to their activity. In this paper, we review the post-translational modifications of FOXOs and their biological functions.
Document Type: Research article
Publication date: 2012-11-01