Abstract:Pharmacogenetics offers new ways of understanding how drugs work and how this affects both the safety and efficacy of drugs in individuals. The potential opportunities are considerable. In drug development, pharmacogenetics shows great potential for improving the efficiency of the drug discovery process, particularly for identifying and validating new drug targets. It is expected to improve the translation of early‐stage projects into medicines that meet public health needs. In clinical care, pharmacogenetics may enable doctors to prescribe more effective interventions and improve their use of evidence‐based medicine. It can help identify those individuals most likely to benefit from a therapy, thereby optimising treatment strategies for both common and complex disorders. It may also enable preventive interventions.
Document Type: Review Article
Publication date: November 1, 2009