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Liver enzyme elevation and normal pulmonary function in an adult with a declining forced expiratory volume in 1 second
Authors: Rider, Nicholas L.; Craig, Timothy J.
Source: Allergy and Asthma Proceedings, Volume 29, Number 3, May-June 2008 , pp. 345-348(4)
Publisher: OceanSide Publications, Inc
Abstract:
This article presents a case report of a 41-year-old male firefighter with cholecystitis and a history of mildly elevated alanine aminotransferase. Liver biopsy showed periodic acid Schiff-positive, diastase-resistant periportal globules. Retrospective review of clinical data revealed progressive lung function decline despite absent pulmonary symptoms and normal pulmonary function testing. The following disorders should be considered in any patient with elevated transaminases without an apparent etiology: viral hepatitides, medication toxicity, autoimmune hepatitis, alcohol-induced hepatic injury, and alpha-1-antitrypsin deficiency.Keywords: Adult; alpha-1-antitrypsin; asymptomatic; hepatitis; liver enzymes; Mmalton; presymptomatic; pulmonary function; transaminases
Document Type: Regular paper
DOI: http://dx.doi.org/10.2500/aap.2008.29.3120
Affiliations: 1: Division of Allergy and Immunology, The Pennsylvania State University Milton S. Hershey Medical Center, Hershey Pennsylvania
Publication date: 2008-05-01
- Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.
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