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Reasons for discontinuation of antiasthma drugs in children with asthma coming from lower socioeconomic classes in a developing country

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Although asthma guidelines recommend regular use of controller therapies in both adults and children with moderate to severe asthma, most of the patients with asthma discontinue antiasthma drugs for various reasons. This study was performed to evaluate the reasons for discontinuation of antiasthma drugs in children with asthma in a developing country and to draw attention to these reasons to increase the adherence of the patients. The study was comprised of 118 children with asthma from lower-income groups who stopped using antiasthma drugs for various reasons. When they visited the hospital for routine or emergency room visits, they were asked for reasons for discontinuing the drugs. The average period for usage of antiasthma drugs ranged between 3 and 16 months (mean, 11.5 months). The most important cause for discontinuation of the drugs was disappearance of the symptoms. The other reasons were as follows: concerns of the parents about the side effects of antiasthma drugs, reluctance of the children to use the drugs, and replacement or discontinuation of the drugs by another physician. Expensiveness of the drugs was another important reason for the lower-income group. These findings suggest that children with asthma may easily discontinue the antiasthma drugs for various reasons. Because of this, both the parents and the children should be educated about long-term use and side effects of antiasthma drugs and warned about the problems of stopping treatment without physician approval.
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Keywords: Antiasthma drugs; asthma; asthma treatment; children; compliance; corticosteroids; cost of asthma treatment; inhaled corticosteroids; long-acting beta-agonists; short-acting beta-agonists; wheezing

Document Type: Research Article

Affiliations: Department of Pediatrics, Sisli Etfal Education and Research Hospital, Istanbul, Turkey

Publication date: 2007-11-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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