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Free Content The pathophysiology of allergic rhinoconjunctivitis

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Allergic rhinitis and conjunctivitis are very common manifestations of allergy affecting 10–30% of adults and up to 40% of children. An improved understanding of the immune and inflammatory mechanisms underlying the pathogenesis of these allergic disorders has provided important insight into the pathogenesis of allergic symptoms related to rhinitis and conjunctivitis, as well as identified potential novel therapeutic targets to interrupt the proinflammatory pathways that contribute to ongoing rhinitis and conjunctivitis symptoms.

Keywords: Allergic conjunctivitis; IL-5; IgE; allergic rhinitis; chemokines; cytokines; eosinophil; histamine; mast cell; toll receptor

Document Type: Research Article


Affiliations: Department of Medicine, University of California San Diego, San Diego, California

Publication date: July 1, 2007

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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