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Resolution of chronic urticaria and angioedema with thyroxine

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Abstract:

Chronic urticaria (CU) is a clinically perplexing condition that not only can compromise the patient's quality of life but also frequently fails to respond satisfactorily to treatment with antiallergy medications such as antihistamines. For a considerable time, CU has been considered a disease of unknown etiology, but in recent years, a wide variety of causes and mechanisms have been suggested. An autoimmune basis linking the role of autoantibodies to thyroid tissue(s) in the pathogenesis of CU has been reported in a limited number of patients with the condition. Once diagnosed, most such cases respond well to the addition of thyroxine to the therapeutic regimen. Nevertheless, the evaluation of CU rarely includes consideration of the causal relationship of autoimmune thyroiditis in CU and inclusion of thyroid autoantibodies in the diagnostic regimen. This case report documents the dramatic improvement of a patient with CU after initiation of thyroxine therapy.

Document Type: Case Report

Publication date: 2005-09-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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