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Chronic Urticaria in Children

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Abstract:

Chronic urticaria (CU) in children often is caused by physical triggers. It also can be associated with autoimmune disease, especially thyroid autoimmunity. Functional autoantibodies against FcRIα have been reported in children with CU but have not been studied in a systematic fashion. The autologous serum skin test has been proposed as a surrogate test to define the presence of these autoantibodies, although it identifies the presence of histamine-releasing factor, not necessarily antibody. Second-generation antihistamines usually are preferred for chronic therapy. Leukotriene receptor antagonists may be of benefit in a subset of children with CU.

Document Type: Research Article

Publication date: January 1, 2005

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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