Allergic Bronchopulmonary Aspergillosis Masquerading as Invasive Pulmonary Aspergillosis

Authors: Coop, CPT Christopher; England, MAJ Ronald W.; Quinn, LTC James M.

Source: Allergy and Asthma Proceedings, Volume 25, Number 4, July-August 2004 , pp. 263-266(4)

Publisher: OceanSide Publications, Inc

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Allergic bronchopulmonary aspergillosis (ABPA) is a noninvasive complex hypersensitivity reaction that occurs in immunocompetent patients with asthma. Aspergillus can invade and disseminate, but this more commonly occurs in severely immunocompromised patients receiving high-dose corticosteroids. We report the case of a 13-year-old immunocompetent male patient with moderate persistent asthma who appeared to have invasive pulmonary aspergillosis on radiographic studies. With further evaluation and workup, it was determined that the patient did not have invasive pulmonary aspergillosis, but that he met the diagnostic criteria for ABPA. Although initially there was a deceptive invasive appearance, proper identification of ABPA facilitated selection of corticosteroid treatment that resulted in prompt clearing of the concerning infiltrates.

Document Type: Research Article

Publication date: July 1, 2004

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  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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