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Anaphylaxis to Insect Sting Associated with Urticaria Pigmentosa

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Anaphylaxis associated with insect stings has been reported to cause ~ 40 deaths per year in the United States. Immunotherapy with venom extracts is a well-established method of treatment of allergy to insect stings. The duration of therapy is based mainly on the initial symptoms and the presence or absence of systemic symptoms during therapy. Evaluation of immunoglobulin E and immunoglobulin G levels as well as repeat skin tests and sting challenges may also provide some additional benefit but are not as useful as the former two criteria. Patients with mastocytosis have a particularly increased risk for anaphylaxis after insect stings. There are many case reports of individuals first diagnosed with mastocytosis after an episode of anaphylaxis after an insect sting, in addition these patients tend to have more severe reactions as well as repeated episodes of systemic reactions during immunotherapy. Early diagnosis of mastocytosis and proper treatment can contribute greatly to the outcome in patients who present with venom allergy.

Document Type: Miscellaneous

Publication date: May 1, 2003

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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