Large airway obstruction can present with symptoms typically associated with asthma, including cough, dyspnea, or wheezing. Obstruction of the large airways should be considered in the differential diagnosis of patients with difficult to manage asthma, particularly those with known risk factors for tracheal disease, atypical clinical features, or lack of response to standard asthma therapy. Spirometry and flow volume loops are valuable diagnostic tools in this evaluation. This article discusses two cases in which large airway obstruction mimicked asthma and reviews the characteristic flow volume loop patterns associated with large airway lesions.
Document Type: Regular Paper
Publication date: March 1, 2003
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Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.
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Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.
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