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Differential Diagnosis of Angioedema

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Angioedema without an associated urticarial syndrome evokes a completely different differential diagnosis from urticaria. This review of the literature discusses hereditary angioedema as prototype of angioedema without urticaria. The review then establishes a differential diagnosis for angioedema, which includes allergic contact dermatitis, connective tissue disease, endocrine associations, parasitic disease, tumor masses, and miscellaneous causes for angioedema. Angioedema without urticaria is a distinct syndrome differing from chronic urticaria. The astute clinician should be familiar with the spectrum of disorders ranging from a functional or quantitative deficiency in C1-esterase inhibitor to a panoply of cutaneous and internal medical disorders. Angioedema without urticaria is a symptom in which there are many different disease mechanisms producing subcutaneous swelling recognizable as angioedema.

Document Type: Research Article

Publication date: 2002-09-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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