The Chemokine Network in Eosinophil Activation
Authors: Elsner, Jörn; Kapp, Alexander
Source: Allergy and Asthma Proceedings, Volume 22, Number 3, May-June 2001 , pp. 139-148(10)
Publisher: OceanSide Publications, Inc
Abstract:Eosinophils are predominant effector cells in allergic and autoimmune diseases attracted by several chemokines into the inflammatory tissue. In the past many new biologically active chemokines have been cloned exploring the gnomic DNA sequence data base in the vicinity of already-known chemokine sequences. This article will help to better understand the chemokine network in eosinophil activation according to the new nomenclature of chemokines. Moreover, possible new therapies, such as chemokine receptor antagonists, for the treatment of allergies are discussed.
Document Type: Research Article
Publication date: 2001-05-01
- Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.
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