Review of Trimellitic Anhydride (TMA) Induced Respiratory Response

$39.50 plus tax (Refund Policy)

Buy Article:


Acid anhydrides such as trimellitic anhydride (TMA) are of interest due to their important industrial uses and to their adverse health effects in exposed populations. Important industrial uses of TMA include the production of epoxy and alkyd resins used to manufacture a variety of coating materials. The adverse health effects are a result of its direct irritant effects on mucosal surfaces in all exposed humans as well as its ability to cause immunologic sensitization in a small proportion of humans. In those individuals who are immunologically sensitized, reexposure to TMA can result in well described immunologic syndromes: asthma-rhinitis, late respiratory systemic syndrome (LRSS), and very rarely pulmonary disease anemia syndrome (PDA). In summary, adverse health effects of TMA are due to its effects as an irritant, an immunologic sensitizer, or a combination of both.

Document Type: Research Article


Publication date: July 1, 1997

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Information for Advertisers
  • Reprint Requests
  • ingentaconnect is not responsible for the content or availability of external websites
Related content



Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more