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Pathophysiology and Therapy for Allergic and Nonallergic Rhinitis: An Updated Review

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Abstract:

Symptoms from rhinitis can be assessed to be more troubling to the patient than symptoms from asthma. Further, the array of bioactive mediators, cytokines, and cells in nasal mucosa suggests that rhinitis is a much more complex condition than formerly thought. The presence of allergic rhinitis is a risk factor for emergence of asthma. Topical nasal corticosteroids have a relatively flat dose-response curve and have onset of action within 1 to 2 days for some patients. Allergen immunotherapy remains the only immunomodulator for patients with allergic rhinitis, with the possible exception of long-term administration of nasal corticosteroids.

Document Type: Research Article

DOI: https://doi.org/10.2500/108854197778594016

Publication date: 1997-07-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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