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Specific Immunotherapy in Asthma

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Abstract:

There is a growing appreciation of asthma as an inflammatory disease. Immunotherapy may playa role in modulating immunologic responses including inflammatory mediator production from cells involved in asthma. Studies of pollen-sensitive asthma have demonstrated beneficial effects of specific immunotherapy for grass, birch, and ragweed pollen-induced asthma. However, risk of systemic reactions exists, especially when specific immunotherapy is administered during the specific allergen season. House dust mite immunotherapy has benefitted asthmatic children more than adults. Patients having unstable pulmonary function may be at the highest risk of having systemic reactions to such immunotherapy. Animal dander immunotherapy and immunotherapy for molds including Clasdosporium and Alternaria may improve selected asthmatic patients. Avoidance of the offending allergen is still, however, the preferred mode of treatment of allergic asthma.

Document Type: Research Article

DOI: https://doi.org/10.2500/108854194778816562

Publication date: 1994-11-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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