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Management of Allergies to Animals

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Abstract:

Allergy to animals affects between 15 to 30% of atopic persons and about the same proportion of all those who work with laboratory animals. The responsible allergens are contained in the urine, saliva, and secretions of furred animals. The allergens apparently dry on fur, bedding, or other fomites so that with disturbance, the antigen becomes airborne on particles or "vectors" of diverse size. Many of these vectors are small enough to remain airborne and reach the lower airway. They adhere to surfaces in the environment such as rugs, walls, and clothing, so that animal allergens are found in virtually every sample of household dust and in the air and surfaces throughout most research facilities. This creates a reservoir of allergen that makes total elimination of the allergen from any environment very difficult. It then becomes important to understand the minimum level of allergen capable of inducing symptoms in sensitized patients so strategies can be developed to reduce exposures to below these limits. Otherwise, management will depend on nearly complete avoidance of animal dander, a difficult task. Alternatively, it will be necessary to modify the allergic host with drugs or immunotherapy.

Document Type: Research Article

DOI: http://dx.doi.org/10.2500/108854192778816942

Publication date: November 1, 1992

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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