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Latex Hypersensitivity: Two Case Reports

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For persons hypersensitive to latex, continued exposure may result in a life-threatening situation. Since 1979 reports appeared supporting evidence of urticaria, rhinitis, asthma, and anaphylaxis in association with latex exposure. We present two cases of latex hypersensitivity, patients who reacted to latex on skin-prick and radioallergosorbent tests (RAST). A 30-year-old surgeon developed reactions to latex gloves. On skin-prick testing to latex extract in saline, he was 4+. RAST latex antigen-specific IgE was 50.75 times control. The second case is that of a 24-year-old nurse who underwent multiple corrective surgeries for congenital birth defects and experienced reactions to latex. On skin-prick testing to an extract of latex in saline, she was 2+. RAST latex antigen-specific IgE was 23.37 times control. Both patients were given epinephrine and diphenhydramine and advised to use latex-free gloves and to avoid latex products. As health care personnel contact with latex products increases because of new guidelines for the prevention of sexually transmitted diseases, more adverse reactions in this subpopulation will occur.
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Document Type: Research Article

Publication date: 01 March 1992

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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