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Allergen-Induced Late Asthmatic Responses and Increased Airway Responsiveness

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Our understanding of the airway response to inhaled allergens has increased substantially over the past several years. In addition to the long-recognized immediate or early asthmatic response, allergens also cause late asthmatic responses and allergen-induced increase in airway responsiveness to nonsensitizing stimuli such as exercise, cold air, histamine, and methacholine. These late sequelae are most likely due to airway inflammation and appear to be more clinically relevant than is the early response in the pathogenesis of clinical atopic allergic asthma.

Document Type: Research Article


Publication date: 1992-01-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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