Management of Patients Allergic to Antimicrobial Drugs

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Abstract:

Allergic reactions to antimicrobial drugs cause significant morbidity in approximately 1% of treated patients. Those who express allergic reactions to antimicrobial drugs or who are at increased risk of reacting also can present difficult diagnostic and management problems. Recent studies suggest that patients who have expressed allergic reactions to antimicrobial drugs in the past or who are the offspring of antimicrobial drug-allergic parents are at increased risk of antimicrobial drug allergy. This propensity to antimicrobial drug allergy is not restricted to specific classes of drug or to specific patterns of allergic reactions. The concept that antimicrobial drug allergy often is a recurrent disease rather than an isolated event has generated new approaches to the comprehensive management of high-risk patients. This concept also has suggested new areas for investigation that may provide fundamental new insights into why some persons express immune responses to haptens and others do not.

Document Type: Research Article

DOI: http://dx.doi.org/10.2500/108854191779114301

Publication date: November 1, 1991

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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