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Immune Mechanisms in Atopic Dermatitis and Relevance to Treatment

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Abstract:

Since the term atopic dermatitis was first introduced in 1933 by Wise and Sulzberger to emphasize the association of eczema with allergic rhinitis and asthma, there has been considerable controversy over the role of allergens in atopic dermatitis. Recent studies suggest that allergens do contribute to the pathogenesis of this disease in at least a subset of patients. An understanding of the immune mechanisms regulating IgE production and the pathogenic events that contribute to the clinical features of this illness may lead to new insights into potential modes of therapy in atopic dermatitis.

Document Type: Research Article

DOI: https://doi.org/10.2500/108854191778879106

Publication date: 1991-09-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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