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Local and Systemic Immune Responses to Food Antigens in Neonates and Infants

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Abstract:

Normal newborns regularly form circulating antibodies to milk proteins by 10 to 14 days of life. Concentrations of these antibodies are influenced by gestational age but not by passive maternal antibody. Secretory antibodies of the IgA and IgM-isotype directed against casein and -lactoglobulin are present in the saliva of normal neonates. SIgA-anti-casein is higher in saliva of newborns at risk to develop atopic disease.

Document Type: Research Article

DOI: https://doi.org/10.2500/108854191778879197

Publication date: 1991-09-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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