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Is the Demonstration of Bronchial Hyperreactivity the Sine Qua Non for Diagnosing Symptomatic Bronchial Asthma?

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Bronchial hyperreactivity, a fundamental feature of bronchial asthma, is universally present in patients with symptomatic asthma. It can be reliably and safely demonstrated in the pulmonary function laboratory through pharmacological bronchoprovocation challenge testing. Furthermore, in the patient suspected of having symptomatic asthma, the laboratory determination of the presence of bronchial hyperreactivity is diagnostically of greater predictive value than findings on history, physical examination, routine spirometry, or the measurement of the total blood eosinophil count.
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Document Type: Research Article

Publication date: 1989-09-01

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  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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