@article {Reisman:1989:1088-5412:97,
title = "Studies of the Natural History of Insect Sting Allergy",
journal = "Allergy and Asthma Proceedings",
parent_itemid = "infobike://ocean/aap",
publishercode ="ocean",
year = "1989",
volume = "10",
number = "2",
publication date ="1989-03-01T00:00:00",
pages = "97-101",
itemtype = "ARTICLE",
issn = "1088-5412",
eissn = "1539-6304",
url = "https://www.ingentaconnect.com/content/ocean/aap/1989/00000010/00000002/art00001",
doi = "doi:10.2500/108854189778960991",
author = "Reisman, Robert E.",
abstract = "The natural history of insect sting allergy was studied by observations of the results of re-sting on two groups of individuals who had prior sting anaphylaxis, had demonstrable venom-specific IgE, and did not receive venom immunotherapy. In the first study group, the mean duration between the initial sting reaction and re-sting exposure was 4.5 years; the re-sting reaction rate was 35%/sting and 50%/patient. In the second long-term study, the mean duration between the sting reaction and re-sting was 7.3 years; the re-sting reaction rate was 12%/sting and 12%/patient. Factors influencing the likelihood of re-sting reaction included older age, and the occurrence of cardiovascular/respiratory anaphylactic symptoms.In a prospective and retrospective study of 133 patients with large local reactions, re-sting observations indicated an extremely high recurrence of similar large local reactions, with little risk of subsequent anaphylaxis.These data suggest that: (1) insect sting anaphylaxis is a self-limiting process for the majority of individuals, and (2) re-stings in individuals who have had large local reactions have a relatively benign prognosis.",
}