Pollen Immunotherapy During Pregnancy: Long-term Follow-up of Offsprings

$39.50 plus tax (Refund Policy)

Buy Article:

Abstract:

The purpose of this study is to determine the long-term affect of maternal pollen immunotherapy on offsprings who are ten years or older. Records of two allergists were reviewed, identifying 63 consecutive pregnant patients who received allergy injections to pollens. Of these patients, 30 returned questionnaires and 23 qualified for this study. A total of 78 offsprings were evaluated. In 40 of these offsprings, (treated group) mean age 16, their mothers had received immunotherapy during pregnancy. In 38 control siblings (untreated offsprings), mean age 22, their mothers had not received immunotherapy during pregnancy. Data on offsprings were obtained by questionnaires and direct interview when skin tested (31% of offspring). Thirty-eight percent (15/40) of treated offsprings and 45% (17/38) of untreated off springs developed asthma/allergic rhinitis. This difference is not statistically significant.

Among the treated offsprings, 69% (9/13) of those skin tested had positive skin tests to one or more pollens administered to the mother while pregnant. Among the untreated offsprings (controls), 55% (6/11) of those skin tested had positive skin tests to one or more pollens administered to the mother during sibling pregnancy. This difference was not statistically significant.

In summary, allergen immunotherapy in pregnancy does not appear to affect the development of asthma/rhinitis or positive skin tests in offsprings.

Document Type: Research Article

DOI: http://dx.doi.org/10.2500/108854188778965591

Publication date: September 1, 1988

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Information for Advertisers
  • Reprint Requests
  • ingentaconnect is not responsible for the content or availability of external websites
Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more