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The Development of Specific IgG4 after Immunotherapy with Standardized Extracts

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A significant reduction in symptoms scores was observed in those patients who elected to continue their immunotherapy after achieving maintenance. All of those patients developed allergen specific IgG4 within a year of post-maintenance injections.

These findings suggest that a reduction of allergic symptoms is accompanied by a rise in specific IgG4 antibody against the offending allergen(s). These specific IgG4 antibodies can be induced by appropriate immunotherapy. Lastly, allergen specific IgG4 antibodies were rapidly and accurately determined using the 3M IgG4 FAST test.

Document Type: Research Article


Publication date: 1987-11-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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