Clinically Relevant Allergens from Laboratory and Domestic Small Animals

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Abstract:

Most of the major allergens that have been isolated from laboratory and domestic animals have been found to be acidic proteins, with molecular weights lower than that of serum albumin (Table II). Recent advances in characterization of antigens from these animals have emphasized that urine and saliva can be as important as epithelia as sources of relevant allergens. Urinary protein allergens are found in mice, rats, guinea pigs and rabbits, whereas cat saliva contains all the major allergens found in cat pelt extract. Urinary proteins from mice, rats and guinea pigs and salivary proteins from cats have been identified in air samples of rooms inhabited by these animals. There is now sufficient immunochemical data to standardize allergens from mice, rats and cats for diagnosis and immunotherapeutic trials.

Document Type: Research Article

DOI: http://dx.doi.org/10.2500/108854187779032479

Publication date: July 1, 1987

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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