Skip to main content

Histamine Receptors in the Lung

Buy Article:

$31.50 plus tax (Refund Policy)

The availability of specific histamine receptor antagonists has provided evidence that human airways have both H1 and H2 receptors. H1 receptors, which mediate bronchoconstriction, predominate. H1 receptor antagonism can produce significant bronchodilatation in some asthmatics, block bronchoconstriction induced by antigen and histamine inhalation challenge, and have some protective effect against exercise and aspirin-induced bronchoconstriction. H1 receptors mediate bronchodilatation, but this effect is relatively weak in man.

The role of classic antihistamines (H1 receptor antagonists) in the treatment of asthma has not been established. Since factors that precipitate asthma are quite varied, these agents may provide benefit in select patients. The availability of new, nonsedating H1 receptor antagonists show some promise in this regard. Future studies may more precisely define their use in asthma therapy.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics

Document Type: Research Article

Publication date: 1987-03-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Information for Advertisers
  • Reprint Requests
  • www.AJRA.com
  • www.AllergyandRhinology.com
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more