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Type I Wheat Ingestion Allergy: A Model of Masked Allergy

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Type I wheat ingestion allergy is a special type of food allergy because the patient usually is not aware of his allergy. The unawareness comes from two reasons; one is that the clinical symptom appears not immediately after ingestion of wheat products but occurs sometime (30–60 min) later, and the other is that it may not appear if the patient does not exercise at this particular time. Therefore, the reaction does not always follow wheat ingestion. The study of enzymatically digested gluten antigens in the patients disclosed that the allergenicity to wheat was reinforced by peptic digestion but abolished by further tryptic digestion, indicating that allergen activity was most potent in the stomach. Anaphylaxis may occur in some patients after wheat ingestion and exercise. Therefore, in exercise-induced anaphylaxis without apparent allergy, one should consider wheat allergy.

Document Type: Research Article


Publication date: January 1, 1987

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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