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The Effect of Aspirin on Serum Immunoglobulins

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After discontinuing aspirin products for seven days, 21 aspirin tolerant adults were given 650 mg of aspirin daily for one week. Serum immunoglobulins (IgG, IgA, IgM, and IgE), complete blood count (CBC), and total eosinophil counts (TEC) were determined before aspirin challenge, four hours after initial challenge, on day seven of aspirin ingestion, 24 hours after discontinuing aspirin, and three weeks after discontinuing aspirin. No significant changes were noted in any of these categories. Although aspirin is an anti-inflammatory drug similar to corticosteroids, it does not produce immunological changes that corticosteroids produce as determined by these parameters.
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Document Type: Research Article

Publication date: 1986-03-01

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  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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