Nasal Polyps and Their Content of Arachidonic Acid Metabolites
Abstract:In three different groups of patients with nasal polyps without or with bronchial hyperreactivity and aspirin-sensitivity the content of several prostaglandin metabolites and LTC4 were measured in the polyp-tissue. A significant elevation of Thromboxan formation (TxB2) was found. The pathophysiological importance of this finding for the development of bronchial hyperreactivity in these patients is seen in context with the non-cholinergic stimulating system with consecutive substance P-formation and the role of the eosinophil cell in chronic inflammation.
Document Type: Research Article
Publication date: 1986-03-01
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