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Marked Peripheral Eosinophilia: A Clue to Allergic Bronchopulmonary Aspergillosis in Office Practice

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Abstract:

Allergic Bronchopulmonary Aspergillosis (ABPA) is not rare. A diagnosis of "clinically probable ABPA" should be suspected in asthmatics who are not well controlled on adequate bronchodilators, who are steroid dependent or who have recurrent pulmonary infiltrates, and who also have a positive skin test with a separate aspergillus extract. Suspicion should also stimulate pursuit of this diagnosis in asthmatics with a total eosinophil count over 500 cells/mm3 or a total serum IgE level over 1,000 IU/ml. Early detection in office practice is feasible, practical, and may be critical to avoidance of permanent pulmonary damage.

Document Type: Research Article

DOI: https://doi.org/10.2500/108854185779109089

Publication date: 1985-09-01

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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