If you are experiencing problems downloading PDF or HTML fulltext, our helpdesk recommend clearing your browser cache and trying again. If you need help in clearing your cache, please click here . Still need help? Email firstname.lastname@example.org
We describe the administration of penicillin for venereal disease in three penicillin-allergic patients or whom alternative antibiotics were not considered suitable. Each patient was skin test negative to the major penicillin determinant benzylpenicilloly-polylysine and a minor determinant mixture of potassium penicillin, benzylpenicilloate and benzylpenicilloyl-n-propylamine provided by the National Institute of Allergy and Infectious Diseases. Therapeutic doses of penicillin were administered without anaphylaxis, but one patient developed serum sickness on day five following benzylpenicillin. The skin testing results were determined within 30 minutes such that penicillin or its derivatives could be administered safely and rapidly to seriously ill patients, i.e. disseminated gonococcemia. When treating neurosyphilis or disseminated gonococcal infection for which non-penicillin therapy is unacceptable, use of the current skin test reagents provides a level of safety in avoiding anaphylaxis not previously attainable.
Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.
The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.
Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.
Articles marked "F" offer free full text for personal noncommercial use only.