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The Epidemic of Acquired Immune Deficiency Syndrome (AIDS)

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Approximately 1200 cases of the epidemic Acquired Immunodeficiency Syndrome have been identified from June 1982 to March 1983. These cases have been reported predominantly from the coastal area of the United States. The principle defect appears to be a defective cell immunity. Characteristic complications include severe opportunistic infections, kaposi's sarcoma, lymphoma, and autoimmune thrombocytopenia. The epidemiologic evidence favors a transmissible agent in blood. Approximately 75% of patients are male homosexuals, 13% are intravenous drug users, 6% Haitian immigrants, a small number of hemophiliacs, young children, and approximately 5% without a clear associated factor. Therapy is directed principally to the infection and neoplasm. There is no specific diagnostic test, and no clear treatment for the underlying immunodeficiency.

Document Type: Research Article

Affiliations: R. A. Cooke Institute of Allergy, St. Luke's – Roosevelt Hospital Center; Division of Allergy & Clinical Immunology, Division of Infectious Dis. & Epidemiology, St. Luke's – Roosevelt Hospital Center; Clinical Medicine, Columbia University College of Physicians & Surgeons

Publication date: 01 March 1983

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