Exercise-Induced Asthma Clinical Aspects and Thoughts Concerning Its Etiology

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Abstract:

Exercise-induced asthma (EIA) occurs in over 80% of patients with clinical asthma, and in up to 40% of patients with allergic rhinitis in whom asthma related to exercise may be their only clinical evidence of bronchial hyper-reactivity. EIA occurs 3-10 minutes after exercise and persists for minutes to hours, usually resolving spontaneously without therapy. The severity of the response is affected by such factors as type and duration of exercise, ambient air temperature, exposure to air-borne allergens and air pollutants.

Exercise-induced asthma can be ameliorated or prevented by beta adrenergic agonists, theophylline, and cromolyn sodium but not by corticosteroids, and its management must be individualized for each patient.

Current evidence suggests that both airway cooling and mediator release are important etiological factors.

Document Type: Research Article

DOI: http://dx.doi.org/10.2500/108854183779068339

Affiliations: University of Washington, Department of Pediatrics and Children's Orthopedic Hospital and Medical Center, Division of Allergy, Seattle, Washington

Publication date: December 1, 1983

More about this publication?
  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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