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Human Monoclonal Antibodies: Immune Complexes and Cryoglobulins

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Of the several types of cryoglobulinemia, those associated with large amounts of monoclonal protein with antibody activity directed against a serum component may behave as an immune complex. The extremely large amount of monoclonal protein and its immune complex nature may allow prolonged activation of inflammatory mediators such as complement. Two discrete syndromes, that of Mixed Cryoglobulinemia and that of anti-albumin monoclonal antibodies are reviewed in this article.

Document Type: Research Article


Publication date: 1982-03-01

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  • Allergy and Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists.

    The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma.

    Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.

    Articles marked "F" offer free full text for personal noncommercial use only.

    The journal is indexed in Thomson Reuters Web of Science and Science Citation Index Expanded, plus the National Library of Medicine's PubMed service.
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